List of publications (from each team)

Partner P1

  • Boutier M, Ronsmans M, Ouyang P, Fournier G, Reschner A, Rakus K, Wilkie G, Farnir F, Bayrou C, Lieffrig F, Li H, Desmecht D, Davison A , A V. 2015 Rational Development of an Attenuated Recombinant Cyprinid Herpesvirus 3 Vaccine using Prokaryotic Mutagenesis and In Vivo Bioluminescent Imaging. PLoS Pathog. accepted with minor revisions.

  • Myster F, Palmeira L, Sorel O, Bouillenne F, DePauw E, Schwartz-Cornil I, Vanderplasschen A, Dewals BG. 2015. Viral semaphorin inhibits dendritic cell phagocytosis and migration but is not essential for gamma-herpesvirus-induced lymphoproliferation in malignant catarrhal fever. J Virol.

  • Ouyang P, Rakus K, van Beurden SJ, Westphal AH, Davison AJ, Gatherer D, Vanderplasschen AF. 2014. IL-10 encoded by viruses: a remarkable example of independent acquisition of a cellular gene by viruses and its subsequent evolution in the viral genome. J Gen Virol 95:245-262.

  • Ronsmans M, Boutier M, Rakus K, Farnir F, Desmecht D, Ectors F, Vandecan M, Lieffrig F, Melard C, Vanderplasschen A. 2014. Sensitivity and permissivity of Cyprinus carpio to cyprinid herpesvirus 3 during the early stages of its development: importance of the epidermal mucus as an innate immune barrier. Vet. Res. 45:100.

  • Machiels B, Stevenson PG, Vanderplasschen A, Gillet L. 2013. A gammaherpesvirus uses alternative splicing to regulate its tropism and its sensitivity to neutralization. PLoS Pathog. 9:e1003753.

  • Ouyang P, Rakus K, Boutier M, Reschner A, Leroy B, Ronsmans M, Fournier G, Scohy S, Costes B, Wattiez R, Vanderplasschen A. 2013. The IL-10 homologue encoded by cyprinid herpesvirus 3 is essential neither for viral replication in vitro nor for virulence in vivo. Vet. Res. 44:53.

  • Rakus K, Ouyang P, Boutier M, Ronsmans M, Reschner A, Vancsok C, Jazowiecka-Rakus J, Vanderplasschen A. 2013. Cyprinid herpesvirus 3: an interesting virus for applied and fundamental research. Vet Res 44:85.

  • Reschner, A., Scohy, S., Vandermeulen, G., Daukandt, M., Jacques, C., Michel, B., Nauwynck, H., Xhonneux, F., Preat, V., Vanderplasschen, A. & Szpirer, C. 2013. Use of Staby((R)) technology for development and production of DNA vaccines free of antibiotic resistance gene. Human vaccines & immunotherapeutics 9, 2203-2210. ULg - UGhent

  • Vidick, S., Leroy, B., Palmeira, L., Machiels, B., Mast, J., Francois, S., Wattiez, R., Vanderplasschen, A. & Gillet, L. (2013). Proteomic characterization of murid herpesvirus 4 extracellular virions. PLoS One 8, e83842.

  • Vrancken R, Boutier M, Ronsmans M, Reschner A, Leclipteux T, Lieffrig F, Collard A, Melard C, Wera S, Neyts J, Goris N, Vanderplasschen A. 2013. Laboratory validation of a lateral flow device for the detection of CyHV-3 antigens in gill swabs. J Virol Methods 193:679-682.

Partner P3

  • Baghi HB, Nauwynck HJ. 2014. Impact of equine herpesvirus type 1 (EHV-1) infection on the migration of monocytic cells through equine nasal mucosa. Comp. Immunol. Microbiol. Infect. Dis. 37:321-329.

  • Reddy VR, Steukers L, Li Y, Fuchs W, Vanderplasschen A, Nauwynck HJ. 2014. Replication characteristics of infectious laryngotracheitis virus in the respiratory and conjunctival mucosa. Avian Pathol 43:450-457.

  • Steukers L, Weyers S, Yang X, Vandekerckhove AP, Glorieux S, Cornelissen M, Van den Broeck W, Temmerman M, Nauwynck HJ. 2014. Mimicking herpes simplex virus 1 and herpes simplex virus 2 mucosal behavior in a well-characterized human genital organ culture. J. Infect. Dis. 210:209-213.

  • Yang X, Steukers L, Forier K, Xiong R, Braeckmans K, Van Reeth K, Nauwynck H. 2014. A Beneficiary Role for Neuraminidase in Influenza Virus Penetration through the Respiratory Mucus. PLoS One 9:e110026.

Partner P4

  • Desimmie B, Weydert C, Schrijvers R, Vets S, Demeulemeester J, Proost P, Paron I, De Rijck J, Mast J, Bannert N, Gijsbers R, Christ F, Debyser Z. 2014. HIV-1 IN/Pol recruits LEDGF/p75 into viral particles. Retrovirology in press.

  • Strating J, van der Linden L, Albulescu L, Bigay J, Arita M, Delang L, Leyssen P, van der Schaar H, Lanke K, Thibaut HJ, Ulferts R, Drin G, Schlinck N, Wubbolts R, Sever N, Head S, Liu J, Beachy PA, De Matteis M, Shair M, Olkkonen M, Neyts J, van Kuppeveld F. 2015. Itraconazole inhibitis enterovirus replication by targeting the oxysterol-binding protein (OSBP). Cell Reports in press.

  • Tijsma A, Thibaut HJ, Dallmeier K, Franco D, van Kuppeveld D, Neyts J. 2015. Hydantoin: the mechanism of its in vitro anti-enterovirus activity revisited. J. Virol. accepted pending revision.

  • van der Linden L, Vives-Adriánc L, Selisko S, Ferrer-Ortac C, Liue X, Lankea K, Ulfertsa R, De Palma A, Tanchis F, Goris N, Lefebvre D, De Clercq C, Leyssen P, Lacroix C, Pürstinger G, Coutard B, Canard B, Boehre B, Arnold J, Cameron C, Verdaguer N, Neyts J, van Kuppeveld F. 2015 The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family. PLoS Pathog. accepted pending minor revisions.

  • Zmurko J, Neyts J, Dallmeier K. 2015. The multifunctional flavivirus NS4b protein: Role in virus replication and immune pathogenesis, and molecular target for the antiviral intervention. Rev. Med. Virol. in press.

  • Borrenberghs D, Thys W, Rocha S, Demeulemeester J, Weydert C, Dedecker P, Hofkens J, Debyser Z, Hendrix J. 2014. HIV virions as nanoscopic test tubes for probing oligomerization of the integrase enzyme. ACS nano 8:3531-3545.

  • De Houwer S, Demeulemeester J, Thys W, Rocha S, Dirix L, Gijsbers R, Christ F, Debyser Z. 2014. The HIV-1 integrase mutant R263A/K264A is 2-fold defective for TRN-SR2 binding and viral nuclear import. J. Biol. Chem. 289:25351-25361.

  • Debyser Z, Christ F, De Rijck J, Gijsbers R. 2014. Host factors for retroviral integration site selection. Trends Biochem. Sci.

  • El Ashkar S, De Rijck J, Demeulemeester J, Vets S, Madlala P, Cermakova K, Debyser Z, Gijsbers R. 2014. BET-independent MLV-based Vectors Target Away From Promoters and Regulatory Elements. Molecular therapy. Nucleic acids 3:e179.

Partner P5

  • Kreit M, Vertommen D, Gillet L, Michiels T. The interferon-inducible mouse Apolipoprotein L9 and prohibitins cooperate to restrict Theiler’s virus replication. PLoS One in revision.

  • Hermant P, Demarez C, Mahlakõiv T, Staeheli P, Meuleman P, Michiels T. 2014. Human but Not Mouse Hepatocytes Respond to Interferon-Lambda In Vivo. PLoS One 9:e87906.

  • Hermant P, Michiels T. 2014. Interferon-lambda in the context of viral infections: production, response and therapeutic implications. J. Innate Immun. 6:563-574.

  • Hermant, P., Francius, C., Clotman, F. & Michiels, T. 2013. IFN-ε is constitutively expressed by cells of the reproductive tract and is inefficiently secreted by fibroblasts and cell lines. PLoS One 8, e71320.

Partner P6

  • Gutierrez G, Rodriguez SM, de Brogniez A, Gillet N, Golime R, Burny A, Jaworski JP, Alvarez I, Vagnoni L, Trono K, Willems L. 2014. Vaccination against delta-retroviruses: the bovine leukemia virus paradigm. Viruses 6:2416-2427.

  • Shiva Shankar TV, Willems L. 2014. Epigenetic modulators mitigate angiogenesis through a complex transcriptomic network. Vascul. Pharmacol. 60:57-66.

  • Gillet NA, Gutierrez G, Rodriguez SM, de Brogniez A, Renotte N, Alvarez I, Trono K, Willems L. 2013. Massive depletion of bovine leukemia virus proviral clones located in genomic transcriptionally active sites during primary infection. PLoS Pathog. 9:e1003687.

  • Vandermeers F, Neelature Sriramareddy S, Costa C, Hubaux R, Cosse JP, Willems L. 2013. The role of epigenetics in malignant pleural mesothelioma. Lung Cancer 81:311-318.

International Partner 1

  • Frederico B, Chao B, May JS, Belz GT, Stevenson PG. 2014. A murid gamma-herpesviruses exploits normal splenic immune communication routes for systemic spread. Cell host & microbe 15:457-470.

  • Frederico B, May JS, Efstathiou S, Stevenson PG. 2014. BAFF receptor deficiency limits gammaherpesvirus infection. J. Virol. 88:3965-3975.

  • Tan CS, Frederico B, Stevenson PG. 2014. Herpesvirus delivery to the murine respiratory tract. J. Virol. Methods 206:105-114.

  • Tan CS, Stevenson PG. 2014. B cell response to herpesvirus infection of the olfactory neuroepithelium. J. Virol. 88:14030-14039.

  • Shivkumar M, Milho R, May JS, Nicoll MP, Efstathiou S, Stevenson PG. 2013. Herpes simplex virus 1 targets the murine olfactory neuroepithelium for host entry. J. Virol. 87:10477-10488.

List of the co-publications

  • Desimmie B, Weydert C, Schrijvers R, Vets S, Demeulemeester J, Proost P, Paron I, De Rijck J, Mast J, Bannert N, Gijsbers R, Christ F, Debyser Z. 2014. HIV-1 IN/Pol recruits LEDGF/p75 into viral particles. Retrovirology in press. K.U.Leuven - Cerva-Coda.

  • Kreit M, Vertommen D, Gillet L, Michiels T. The interferon-inducible mouse Apolipoprotein L9 and prohibitins cooperate to restrict Theiler’s virus replication. PLoS One in revision. ULg – UCL.

  • Reddy VR, Steukers L, Li Y, Fuchs W, Vanderplasschen A, Nauwynck HJ. 2014. Replication characteristics of infectious laryngotracheitis virus in the respiratory and conjunctival mucosa. Avian Pathol 43:450-457.

  • Machiels, B., Stevenson, P. G., Vanderplasschen, A. & Gillet, L. 2013. A gammaherpesvirus uses alternative splicing to regulate its tropism and its sensitivity to neutralization. PLoS Pathog 9, e1003753. ULg – University of Cambridge.

  • Vidick S, Leroy B, Palmeira L, Machiels B, Mast J, Francois S, Wattiez R, Vanderplasschen A, Gillet L. 2013. Proteomic characterization of murid herpesvirus 4 extracellular virions. PLoS One 8:e83842. ULg – Cerva Coda.

  • Vrancken, R., Boutier, M., Ronsmans, M., Reschner, A., Leclipteux, T., Lieffrig, F., Collard, A., Melard, C., Wera, S., Neyts, J., Goris, N. & Vanderplasschen, A. 2013. Laboratory validation of a lateral flow device for the detection of CyHV-3 antigens in gill swabs. J Virol Methods 193, 679-682. ULg - K.U.Leuven.

  • Reschner, A., Scohy, S., Vandermeulen, G., Daukandt, M., Jacques, C., Michel, B., Nauwynck, H., Xhonneux, F., Preat, V., Vanderplasschen, A. & Szpirer, C. 2013. Use of Staby((R)) technology for development and production of DNA vaccines free of antibiotic resistance gene. Human vaccines & immunotherapeutics 9, 2203-2210. ULg - UGhent.

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